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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This antibody is specific for human Cytochrome b245 light chain aa 29-33 (TAGRF) and 183-188 (PQVNPI). The immunogen was prepared using partially purified human neutrophil flavocytochrome b (heparin Ultrogel/lectin affinity purification in Triton X-100).
This target has a predicted molecular weight of 21 kDa.
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cytochrome b(558) alpha chain; Cytochrome b-245 light chain; Cytochrome b558 subunit alpha; Neutrophil cytochrome b 22 kDa polypeptide; p22 phagocyte B-cytochrome; p22-phox; p22phox; Superoxide-generating NADPH oxidase light chain subunit
基因别名: CYBA
Entrez Gene ID: (Human) 1535