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Invitrogen
CYP2C9 Monoclonal Antibody (OTI1D7)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-25745
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI1D7
抗原
Full length human recombinant protein of CYP2C9 produced in HEK293T cell
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytochrome P-450 S-mephenytoin 4-hydroxylase; cytochrome P-450MP; cytochrome P450 PB-1; cytochrome P450, family 2, subfamily C, polypeptide 9; flavoprotein-linked monooxygenase; MGC149605; MGC88320; microsomal monooxygenase; unnamed protein product; xenobiotic monooxygenase
基因别名: CPC9; CYP2C; CYP2C10; CYPIIC9; P450-2C9; P450IIC9
UniProt ID: (Human) P11712
Entrez Gene ID: (Human) 1559
monooxygenase activity
iron ion binding
arachidonic acid epoxygenase activity
steroid hydroxylase activity
arachidonic acid 14,15-epoxygenase activity
arachidonic acid 11,12-epoxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
(S)-limonene 6-monooxygenase activity
(S)-limonene 7-monooxygenase activity
heme binding
caffeine oxidase activity
(R)-limonene 6-monooxygenase activity
estrogen 2-hydroxylase activity
arachidonate 8,9-epoxygenase activity
fatty acid omega-1 hydroxylase activity
terpenoid metabolic process
xenobiotic metabolic process
steroid metabolic process
cholesterol metabolic process
estrogen metabolic process
monoterpenoid metabolic process
arachidonic acid metabolic process
epoxygenase P450 pathway
urea metabolic process
monocarboxylic acid metabolic process
xenobiotic catabolic process
long-chain fatty acid biosynthetic process
icosanoid biosynthetic process
oxidative demethylation
cellular organofluorine metabolic process
omega-hydroxylase P450 pathway
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