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Invitrogen
CYP39A1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-106814
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CYP39A1(Accession Q9NYL5), corresponding to amino acid residues L365-P415.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Cytochrome P450 39A1.
靶标信息
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 24-hydroxycholesterol 7-alpha-hydroxylase; Cytochrome P450 39A1; cytochrome P450, 39a1 (oxysterol 7alpha-hydroxylase); mCYP39A1; Oxysterol 7-alpha-hydroxylase
基因别名: Cyp39a1; mCYP39A1
UniProt ID: (Mouse) Q9JKJ9
Entrez Gene ID: (Mouse) 56050
monooxygenase activity
iron ion binding
steroid 7-alpha-hydroxylase activity
oxysterol 7-alpha-hydroxylase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
heme binding
24-hydroxycholesterol 7alpha-hydroxylase activity
metal ion binding
oxygenase
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