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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive test controls include: A-549, HT-29, Mouse liver, Mouse lung, Rat liver. The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein.
Immunogen sequence: KVISFLTKSV KQIKEGRLKE TQKHRVDFLQ LMIDSQNSKD SETHKALSDL ELMAQSIIFI FAGYETTSSV LSFIIYELAT HPDVQQKVQK EIDTVLPNKA PPTYDTVLQL EYLDMVVNET LRLFPVAMRL ERVCKKDVEI NGMFIPKGVV VMIPSYVLHH DPKYWTEPEK FLPERFSKKN KDNIDPYIYT PFGSGPRNCI GMRFALVNMK LALVRVLQNF SFKPCKETQI PLKLRFGGLL LTEKPIVLKA ESRDETVSGA
This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CYPIIIA7; Cytochrome P450 3A7; Cytochrome P450-HFLA; P450HLp2
基因别名: CYP3A7
Entrez Gene ID: (Human) 1551