Search

  • 联系我们
  • 货号直购

Invitrogen

CaMKII Pan Recombinant Rabbit Monoclonal Antibody (K01_4N16)

查看其他7个CaMKII Pan抗体

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

说明书
Certificates
实验方案
问题与答案
技术支持
说明书
Certificates
实验方案
问题与答案
技术支持
说明书
Certificates
实验方案
问题与答案
技术支持
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}

产品信息

MA567442

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:1,000
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293F

分类

Recombinant Monoclonal

类型

Antibody

克隆号

K01_4N16

抗原

A synthesized peptide derived from human CaMKII.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

规格

100 µg

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 50% glycerol, 0.05% BSA, 150mM NaCl

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+/calmodulin (CaM) binding and autophosphorylation and has been implicated in regulation of the cell cycle and transcription. It is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
Cite this product

生物信息学

蛋白别名: alpha CaM kinase II; alpha-CaMKII; alpha-KAP; alternatively spliced; association domain; beta M CaM kinase II; brain type II Ca2+/calmodulin-dependent protein kinase beta subunit; Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II beta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; Ca+2/calmodulin-dependent protein kinase II gamma; Ca2+/calmodulin-dependent protein kinase II; Ca2+/calmodulin-dependent protein kinase II alpha; Calcium, calmodulin-dependent protein kinase; Calcium, calmodulin-dependent protein kinase II; Calcium, calmodulin-dependent protein kinase, type II; calcium-calmodulin-dependent protein kinase II; calcium/calmodulin-dependent protein kinase; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; calcium/calmodulin-dependent protein kinase II alpha subunit; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II delta chain; calcium/calmodulin-dependent protein kinase type II gamma chain; calcium/calmodulin-dependent protein kinase type II subunit gamma-like; calmodulin-dependent protein kinase II gamma subunit (EC 2.7.1.37); calmodulin-dependent protein kinase II-delta (EC 2.7.1.37); CaM kinase II; CaM kinase II alpha subunit; CaM kinase II beta subunit; CaM kinase II delta subunit; caM kinase II subunit alpha; caM kinase II subunit beta; caM kinase II subunit delta; caM kinase II subunit gamma; CaM-kinase II alpha chain; CaM-kinase II beta chain; CaM-kinase II delta chain; caM-kinase II gamma chain; CaMK II; CaMK-II alpha subunit; CaMK-II delta subunit; caMK-II subunit alpha; caMK-II subunit beta; caMK-II subunit delta; caMK-II subunit gamma; Camk2 gamma; proline rich calmodulin-dependent protein kinase; protein kinase homolog; unnamed protein product

查看更多 收起

基因别名: 2810011D23Rik; 8030469K03Rik; [d]-CaMKII; CAM2; CAMK; CaMK II; CAMK-II; CAMK1; CAMK2; CAMKA; CAMKB; CAMKD; CAMKG; Camki; CaMKII; CaMKIIalpha; CaMKIIbeta; CaMKIINalpha; Ck2b; mKIAA0968; MRD53; MRD54; MRD59; MRT63; PK2CDD; PKCCD; RATCAMKI

查看更多 收起

UniProt ID: (Human) Q9UQM7, (Human) Q13554, (Human) Q13557, (Human) Q13555, (Mouse) P11798, (Rat) P11275, (Rat) P08413, (Mouse) P28652, (Rat) P15791, (Mouse) Q6PHZ2, (Mouse) Q923T9, (Rat) P11730

查看更多 收起

Entrez Gene ID: (Human) 815, (Human) 816, (Human) 817, (Human) 818, (Mouse) 12322, (Rat) 25400, (Rat) 24245, (Mouse) 12323, (Rat) 24246, (Mouse) 108058, (Mouse) 12325, (Rat) 171140

查看更多 收起

功能
protein kinase activity protein serine/threonine kinase activity calmodulin-dependent protein kinase activity protein binding calmodulin binding ATP binding glutamate receptor binding identical protein binding protein homodimerization activity protein serine kinase activity sodium channel inhibitor activity titin binding ion channel binding calcium-dependent protein serine/threonine phosphatase activity kinase activity GTPase activating protein binding protein kinase binding phospholipase binding structural constituent of postsynaptic actin cytoskeleton nitric-oxide synthase binding
参与通路
regulation of cell growth regulation of the force of heart contraction regulation of membrane depolarization regulation of transcription from RNA polymerase II promoter protein phosphorylation regulation of heart contraction positive regulation of cardiac muscle hypertrophy regulation of cell communication by electrical coupling positive regulation of cardiac muscle cell apoptotic process regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion endoplasmic reticulum calcium ion homeostasis regulation of neuronal synaptic plasticity relaxation of cardiac muscle long-term synaptic potentiation regulation of ryanodine-sensitive calcium-release channel activity regulation of cellular localization cellular response to calcium ion cardiac muscle cell contraction regulation of heart rate by cardiac conduction regulation of cardiac muscle cell action potential regulation of cardiac muscle cell action potential involved in regulation of contraction regulation of cell communication by electrical coupling involved in cardiac conduction regulation of relaxation of cardiac muscle negative regulation of sodium ion transmembrane transport regulation of calcium ion transmembrane transport via high voltage-gated calcium channel regulation of protein localization to plasma membrane G1/S transition of mitotic cell cycle response to ischemia calcium ion transport JAK-STAT cascade peptidyl-serine phosphorylation ionotropic glutamate receptor signaling pathway cellular response to interferon-beta angiotensin-activated signaling pathway positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of JAK-STAT cascade protein autophosphorylation regulation of neurotransmitter secretion dendrite morphogenesis positive regulation of calcium ion transport dendritic spine development cellular response to interferon-gamma regulation of neurotransmitter receptor localization to postsynaptic specialization membrane neurotransmitter receptor transport to plasma membrane negative regulation of ferroptosis regulation of mitochondrial membrane permeability involved in apoptotic process peptidyl-threonine autophosphorylation regulation of endocannabinoid signaling pathway regulation of neuron migration inhibitory G-protein coupled receptor phosphorylation positive regulation of phospholipase activity positive regulation of neuron projection development regulation of synaptic transmission, cholinergic response to cadmium ion regulation of long-term neuronal synaptic plasticity neuromuscular process controlling balance activation of meiosis involved in egg activation positive regulation of dendritic spine morphogenesis regulation of synapse maturation positive regulation of synapse maturation postsynaptic actin cytoskeleton organization hippocampal neuron apoptotic process cellular response to homocysteine response to psychosocial stress positive regulation of apoptotic signaling pathway signal transduction regulation of skeletal muscle adaptation regulation of synapse structural plasticity regulation of calcium ion transport regulation of dendritic spine development response to hypoxia response to oxidative stress regulation of neuron projection development regulation of postsynaptic membrane neurotransmitter receptor levels regulation of sodium ion transport positive regulation of G2/M transition of mitotic cell cycle positive regulation of smooth muscle cell migration cellular potassium ion homeostasis positive regulation of Rac protein signal transduction cardiac muscle contraction cell growth involved in cardiac muscle cell development positive regulation of ERK1 and ERK2 cascade positive regulation of vascular smooth muscle cell proliferation positive regulation of DNA biosynthetic process insulin secretion
guarantee_icon

性能保障

只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。*

了解更多
help_icon

随时为您服务

获取常见问题的专家解答，或者直接联系我们的技术专家，咨询应用、设备、常规产品使用问题。

联系技术支持