Invitrogen

CaMKII delta Recombinant Rabbit Monoclonal Antibody (10M1P2)

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说明书
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CaMKII delta Recombinant Rabbit Monoclonal Antibody (10M1P2)

产品信息

MA5-35778

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:1,000-1:6,000
-

免疫细胞化学 (ICC/IF)

1:50-1:200
-

酶联免疫吸附实验 (ELISA)

1 µg/mL
-
产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

10M1P2

抗原

Synthetic Peptide
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.4 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2849678

产品详细信息

Immunogen sequence: MASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE

靶标信息

CaMKII delta belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase type II delta chain; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II delta subunit; CaM kinase II subunit delta; CaM-kinase II delta chain; CAM2; CaMK-II delta subunit; caMK-II subunit delta; CAMK2B; CAMK2G; CAMKB; CAMKG

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基因别名: 2810011D23Rik; 8030469K03Rik; [d]-CaMKII; CaMK II; CAMK2D; CAMKD; Kiaa4163

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UniProt ID: (Human) Q13557, (Mouse) Q6PHZ2

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Entrez Gene ID: (Human) 817, (Mouse) 108058

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功能
protein serine/threonine kinase activity calmodulin-dependent protein kinase activity Ras guanyl-nucleotide exchange factor activity protein binding calmodulin binding ATP binding sodium channel inhibitor activity titin binding protein homodimerization activity ion channel binding nitric-oxide synthase binding nucleotide binding protein kinase activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups non-receptor serine/threonine protein kinase
参与通路
G1/S transition of mitotic cell cycle MAPK cascade regulation of cell growth response to hypoxia regulation of the force of heart contraction regulation of membrane depolarization regulation of transcription from RNA polymerase II promoter protein phosphorylation calcium ion transport regulation of heart contraction regulation of G2/M transition of mitotic cell cycle positive regulation of cardiac muscle hypertrophy regulation of cell communication by electrical coupling positive regulation of cardiac muscle cell apoptotic process regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion positive regulation of smooth muscle cell migration peptidyl-serine phosphorylation peptidyl-threonine phosphorylation cellular potassium ion homeostasis endoplasmic reticulum calcium ion homeostasis positive regulation of Rac protein signal transduction positive regulation of GTPase activity protein autophosphorylation positive regulation of smooth muscle cell proliferation protein oligomerization relaxation of cardiac muscle regulation of ryanodine-sensitive calcium-release channel activity interferon-gamma-mediated signaling pathway regulation of cellular localization cell growth involved in cardiac muscle cell development positive regulation of ERK1 and ERK2 cascade cellular response to calcium ion cardiac muscle cell contraction regulation of heart rate by cardiac conduction regulation of cardiac muscle cell action potential regulation of cardiac muscle cell action potential involved in regulation of contraction regulation of cellular response to heat regulation of histone deacetylase activity regulation of cell communication by electrical coupling involved in cardiac conduction regulation of relaxation of cardiac muscle negative regulation of sodium ion transmembrane transport regulation of calcium ion transmembrane transport via high voltage-gated calcium channel negative regulation of sodium ion transmembrane transporter activity regulation of sodium ion transport phosphorylation cardiac muscle contraction
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