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Invitrogen
CaMKII delta Monoclonal Antibody (GT4811)
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CaMKII delta Antibody (MA5-27735) in WB
Western Blot analysis of CaMKII delta was performed by separating 30 µg of non-transfected (–) and transfected (+) 293T whole cell extracts by 10% SDS-PAGE. Proteins were transferred to a membrane and probed with a CaMKII delta Monoclonal Antibody (GT4811) (Product # MA5-27735) at a dilution of 1:5000. The HRP-conjugated anti-mouse IgG antibody was used to detect the primary antibody.
产品信息
MA5-27735
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rabbit
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
GT4811
抗原
Recombinant protein encompassing a sequence within the center region of human CaMKII. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.69 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: U87-MG, SK-N-SH, Neuro 2A, C8D30, NIH-3T3, mouse brain, rat brain, transfected 293T
Predicted Reactivity: Xenopus laevis (94%), Pig (100%), Rabbit (99%), Chicken (98%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
CaMKII delta belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II delta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase type II delta chain; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II delta subunit; CaM kinase II subunit delta; CaM-kinase II delta chain; CAM2; CaMK-II delta subunit; caMK-II subunit delta; CAMK2B; CAMK2G; CAMKB; CAMKG
基因别名: 2810011D23Rik; 8030469K03Rik; [d]-CaMKII; CaMK II; CAMK1; Camk2; CAMK2D; CAMKD; Camki; Kiaa4163; RATCAMKI
UniProt ID: (Human) Q13557, (Rat) P15791, (Mouse) Q6PHZ2
Entrez Gene ID: (Human) 817, (Rat) 24246, (Mouse) 108058
protein serine/threonine kinase activity
calmodulin-dependent protein kinase activity
Ras guanyl-nucleotide exchange factor activity
protein binding
calmodulin binding
ATP binding
sodium channel inhibitor activity
titin binding
protein homodimerization activity
ion channel binding
nitric-oxide synthase binding
nucleotide binding
protein kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
G1/S transition of mitotic cell cycle
MAPK cascade
regulation of cell growth
response to hypoxia
regulation of the force of heart contraction
regulation of membrane depolarization
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
calcium ion transport
regulation of heart contraction
regulation of G2/M transition of mitotic cell cycle
positive regulation of cardiac muscle hypertrophy
regulation of cell communication by electrical coupling
positive regulation of cardiac muscle cell apoptotic process
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
positive regulation of smooth muscle cell migration
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
cellular potassium ion homeostasis
endoplasmic reticulum calcium ion homeostasis
positive regulation of Rac protein signal transduction
positive regulation of GTPase activity
protein autophosphorylation
positive regulation of smooth muscle cell proliferation
protein oligomerization
relaxation of cardiac muscle
regulation of ryanodine-sensitive calcium-release channel activity
interferon-gamma-mediated signaling pathway
regulation of cellular localization
cell growth involved in cardiac muscle cell development
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
cardiac muscle cell contraction
regulation of heart rate by cardiac conduction
regulation of cardiac muscle cell action potential
regulation of cardiac muscle cell action potential involved in regulation of contraction
regulation of cellular response to heat
regulation of histone deacetylase activity
regulation of cell communication by electrical coupling involved in cardiac conduction
regulation of relaxation of cardiac muscle
negative regulation of sodium ion transmembrane transport
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
negative regulation of sodium ion transmembrane transporter activity
regulation of sodium ion transport
cardiac muscle contraction
phosphorylation
