Alomone Labs, LTD

CaV1.3 (CACNA1D) Polyclonal Antibody

Name: CaV1.3 (CACNA1D) Polyclonal Antibody
Brand: Alomone Labs, LTD
SKU: ACC-005-GP200UL

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说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

CaV1.3 (CACNA1D) Antibody in Immunohistochemistry (IHC)

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CaV1.3 (CACNA1D) Antibody (ACC-005-GP200UL) in IHC

Expression of CaV1.3 in rat DRGs - Immunohistochemical staining of rat dorsal root ganglion (DRG) using Guinea pig Anti-CaV1.3 (CACNA1D) Antibody (#ACC-005-GP), (1:200). A. CaV1.3 staining (red) is detected in some DRG cells (arrows). B. Nuclei staining using DAPI as the counterstain. C. Merged image of panels A and B.

CaV1.3 (CACNA1D) Antibody in Western Blot (WB)

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Immunogen image

Immunogen Image CaV1.3 (CACNA1D) Polyclonal Antibody

产品信息

ACC-005-GP200UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

免疫组化 (IHC)

1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Guinea pig / IgG

分类

Polyclonal

类型

Antibody

抗原

(C)DNKVTIDDYQEEAEDKD, corresponding to amino acid residues 859-875 of rat CaV1.3, Intracellular loop between domains II and III

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.85 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

靶标信息

CACNA1D is also known as PASNA, SANDD or Cav1. 3. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: brain class D; CACNA 1D; calcium channel alpha-1 subunit; Calcium channel, L type, alpha-1 polypeptide isoform 2; Calcium channel, L type, alpha-1 polypeptide, isoform 2; calcium channel, neuroendocrine/brain-type, alpha 1 subunit; calcium channel, voltage-dependent, L type, alpha 1D subunit; CaV1.3alpha1; RBD; voltage-dependent calcium channel subunit alpha1D; Voltage-dependent L-type calcium channel subunit alpha-1D; voltage-gated calcium channel alpha 1 subunit; voltage-gated calcium channel alpha subunit Cav1.3; voltage-gated calcium channel pore forming subunit CaV1.3alpha1 IVS3-IVS4 extracellular linker; Voltage-gated calcium channel subunit alpha Cav1.3

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基因别名: 8430418G19Rik; C79217; CACH3; CACN4; CACNA1D; CACNL1A2; Cav1.3; Cchl1a; CCHL1A2; D-LTCC; PASNA; SANDD

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UniProt ID: (Human) Q01668, (Mouse) Q99246

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Entrez Gene ID: (Human) 776, (Mouse) 12289, (Rat) 29716

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