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Invitrogen
Caffeine Monoclonal Antibody (F1-P2B1G1)
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产品信息
MA5-14725
应用
建议稀释比
已发表文章
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
F1-P2B1G1
抗原
Caffeine-3-KLH
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Ion-exchange chromatography
保存液
PBS, pH 7.4, with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-14725 targets Caffeine in ELISA, IP, and RIA applications and shows reactivity with Chemical samples.
The MA5-14725 immunogen is caffeine-3-KLH.
Product MA514725 is a smaller package size of MIC0401 (formerly sold as a Seradyn product).
靶标信息
Caffeine is a methylxanthine alkaloid found in the seeds, nuts, or leaves of a number of plants native to South America and East Asia that is structurally related to adenosine and acts primarily as an adenosine receptor antagonist with psychotropic and anti-inflammatory activities. Upon ingestion, caffeine binds to adenosine receptors in the central nervous system (CNS), which inhibits adenosine binding. This inhibits the adenosine-mediated downregulation of CNS activity; thus, stimulating the activity of the medullary, vagal, vasomotor, and respiratory centers in the brain. This agent also promotes neurotransmitter release that further stimulates the CNS. The anti-inflammatory effects of caffeine are due the nonselective competitive inhibition of phosphodiesterases (PDEs). Inhibition of PDEs raises the intracellular concentration of cyclic AMP (cAMP), activates protein kinase A, and inhibits leukotriene synthesis, which leads to reduced inflammation and innate immunity. [National Center for Biotechnology Information. PubChem Compound Database; CID=2519].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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