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Invitrogen
Calbindin D28K Monoclonal Antibody (401025)
高级验证
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
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Calbindin D28K Antibody (MA5-24135) in IHC (P)
Immunohistochemical analysis of Calbindin D28K in immersion fixed paraffin-embedded sections of human brain (cerebellum). Samples were incubated in Calbindin D28K monoclonal antibody (Product # MA5-24135) using a dilution of 25 µg/mL overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue).
产品信息
MA5-24135
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Mouse
/ IgG2B
分类
Monoclonal
类型
Antibody
克隆号
401025
抗原
E. coli-derived recombinant human Calbindin D Met1-Asn261
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609695
产品详细信息
In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human S100P.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Calbindin; calbindin 1, (28kD); calbindin 1, 28kDa; Calbindin D28; D-28K; RTVL-H protein; Vitamin D-dependent calcium-binding protein, avian-type
基因别名: CAB27; CALB; CALB1; D-28K
UniProt ID: (Human) P05937
Entrez Gene ID: (Human) 793
short-term memory
long-term memory
locomotory behavior
retina layer formation
metanephric part of ureteric bud development
regulation of synaptic plasticity
regulation of cytosolic calcium ion concentration
cellular response to organic substance
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
