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Invitrogen
Calbindin D28K Recombinant Rabbit Monoclonal Antibody (5H25L2)
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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Calbindin D28K Antibody (702411) in ICC/IF
For immunofluorescence analysis, PC12 cells were fixed and permeabilized for detection of endogenous Calbindin D using Anti- Calbindin D Recombinant Rabbit Monoclonal Antibody (Product # 702411, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection... View More
产品信息
702411
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5H25L2
抗原
Protein corresponding to Human CALB1 (aa 1-261)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2633088
产品详细信息
This antibody is predicted to react with Monkey, Horse and Cat
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calbindin; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; Calbindin D28; calbindin-28K; calbindin-D (28k); CalbindinD28K; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; D-28K; PCD-29; RTVL-H protein; Spot 35 protein; Vitamin D-dependent calcium-binding protein, avian-type
基因别名: Brain-2; CAB27; CaBP28K; CALB; Calb-1; CALB1; CB; D-28K
UniProt ID: (Human) P05937, (Rat) P07171, (Mouse) P12658
Entrez Gene ID: (Human) 793, (Rat) 83839, (Mouse) 12307
short-term memory
long-term memory
locomotory behavior
retina layer formation
metanephric part of ureteric bud development
regulation of synaptic plasticity
regulation of cytosolic calcium ion concentration
cellular response to organic substance
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
learning or memory
vitamin D metabolic process
calcium ion homeostasis
