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Invitrogen
Cannabinoid Receptor 1 (Biosimilar) Recombinant Human Monoclonal Antibody
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Cannabinoid Receptor 1 (Biosimilar) Antibody (MA5-58827) in Flow
Flow cytometry analysis of Cannabinoid Receptor 1 (Biosimilar) Recombinant monoclonal antibody (Product # MA5-58827). Human CB1/CNR1 EGFP HEK293 Cell Line were stained with (GFB-024) and negative control protein respectively, washed and then followed by APC and analyzed with FACS, EC50=0.007 µg/mL.
产品信息
MA5-58827
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
形式
Lyophilized
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
25mM histidine, pH 6.2, with 8% sucrose, 0.01% Tween 80
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
This antibody can also be cross referenced by the term GFB-024.
靶标信息
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB-R; CB1 receptor; central cannabinoid receptor; HGNC:2159; N-terminal variant; OTTHUMP00000016839; RP1-23D17.1; unnamed protein product
基因别名: CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR; CNR1
UniProt ID: (Human) P21554
Entrez Gene ID: (Human) 1268
signal transduction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
axonal fasciculation
cannabinoid signaling pathway
glucose homeostasis
retrograde trans-synaptic signaling by endocannabinoid
regulation of presynaptic cytosolic calcium ion concentration
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