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Invitrogen
Capsaicin Recombinant Mouse Monoclonal Antibody (5G8)
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Capsaicin Antibody (MA566599) in SDS-PAGE
SDS-PAGE characterization of Capsaicin under reducing conditions. Lane M: Protein marker (kDa); Lane CPS: Purified Capsaicin Recombinant Monoclonal (Product # MA566599). Capsaicin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-268.
产品信息
MA566599
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5G8
抗原
Conjugate of CPS hapten and KLH.
偶联物
形式
Liquid
浓度
6 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Capsaicin is an active component of chili peppers, belonging to the Capsicum genus, and is responsible for their characteristic pungency. It is a naturally occurring alkaloid that interacts with the transient receptor potential vanilloid 1 (TRPV1) receptor, a protein on the surface of sensory neurons. Activation of TRPV1 by capsaicin leads to the sensation of heat and pain, which is why it imparts a "hot" taste when consumed. Capsaicin is used in various applications due to its diverse physiological effects; it serves as an analgesic in topical ointments and patches for relieving pain from conditions such as arthritis, neuropathy, and muscle strains. Additionally, capsaicin is studied for its potential metabolic benefits, including increased thermogenesis and fat oxidation, which may aid in weight management. The compound also exhibits antimicrobial properties and is explored for its role in cancer therapy due to its ability to induce apoptosis in certain cancer cell lines. While beneficial, capsaicin can cause irritation upon contact, necessitating careful handling in concentrated forms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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