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Invitrogen
Carabin Polyclonal Antibody
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产品信息
PA5-84823
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DLVQPPELQD DSSSLGSDSE LSGPGPYRQA DRYGFIGGSS AEPGPGHPPA DLIRQREMKW VEM
Highest antigen sequence indentity to the following orthologs: Rat - 84%, Mouse - 76%.
靶标信息
Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Carabin; TBC1 domain family member 10C; TBC1 domain family, member 10C
基因别名: CARABIN; EPI64C; TBC1D10C
UniProt ID: (Human) Q8IV04
Entrez Gene ID: (Human) 374403
intracellular protein transport
regulation of vesicle fusion
retrograde transport, endosome to Golgi
negative regulation of B cell activation
negative regulation of NFAT protein import into nucleus
negative regulation of ERK1 and ERK2 cascade
activation of GTPase activity
regulation of cilium assembly
