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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human Carbonic Anhydrase III/CA3.
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10. 3 kb and contains seven exons and six introns.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CA III; CA-III; CAH3; CAIII (Muscle); Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III; carbonic anhydrase III, muscle specific; EC 4.2.1.1; epididymis secretory sperm binding protein Li 167mP; HEL-S-167mP
基因别名: CA3; CAIII; Car3
UniProt ID: (Human) P07451
Entrez Gene ID: (Human) 761