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Invitrogen
Carboxypeptidase E Polyclonal Antibody
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Carboxypeptidase E Antibody (PA5-101497) in ICC/IF
Immunofluorescent analysis of Carboxypeptidase E in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with Carboxypeptidase E polyclonal antibody (Product # PA5-101497) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-101497
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CPE(Accession P16870), corresponding to amino acid residues P273-P323.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CPE.
靶标信息
This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: carbocypeptidase E; Carboxypeptidase E; Carboxypeptidase H; CarboxypeptidaseE; CarboxypeptidaseH; CBPE; cobalt-stimulated chromaffin granule carboxypeptidase; CPE; CPH; Cph 1; Enkephalin convertase; epididymis secretory sperm binding protein; insulin granule-associated carboxypeptidase; Prohormone-processing carboxypeptidase; unnamed protein product
基因别名: BDVS; CARBE; CPE; CPH; Cph-1; Cph1; fat; IDDHH; R74677
UniProt ID: (Rat) P15087, (Mouse) Q00493
Entrez Gene ID: (Human) 1363, (Rat) 25669, (Mouse) 12876
cardiac left ventricle morphogenesis
proteolysis
peptide metabolic process
cell communication
neuropeptide signaling pathway
protein localization
Wnt signaling pathway
protein processing
signaling
protein modification process
protein localization to membrane
peptide hormone processing
insulin processing
enkephalin processing
peptide catabolic process
negative regulation of branching morphogenesis of a nerve
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