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Invitrogen
Carboxypeptidase E Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-77027
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human Carboxypeptidase E.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: carbocypeptidase E; carboxypeptidase E (EC 3.4.17.10); carboxypeptidase H; carboxypeptidase H precursor (EC 3.4.17.10); CarboxypeptidaseE; CarboxypeptidaseH; CBPE; cobalt-stimulated chromaffin granule carboxypeptidase; Cph 1; enkephalin convertase; epididymis secretory sperm binding protein; insulin granule-associated carboxypeptidase; prohormone-processing carboxypeptidase; unnamed protein product
基因别名: BDVS; CARBE; CPH; Cph-1; Cph1; fat; IDDHH; NF-alpha1
UniProt ID: (Human) P16870, (Rat) P15087, (Mouse) Q00493
Entrez Gene ID: (Human) 1363, (Rat) 25669, (Mouse) 12876
cardiac left ventricle morphogenesis
proteolysis
peptide metabolic process
cell communication
neuropeptide signaling pathway
protein localization
Wnt signaling pathway
protein processing
signaling
protein modification process
protein localization to membrane
neuron migration
peptide hormone processing
insulin processing
peptide hormone secretion
protein localization to secretory granule
enkephalin processing
insulin secretion involved in cellular response to glucose stimulus
peptide catabolic process
cellular response to hydrogen peroxide
cellular response to dexamethasone stimulus
cellular response to staurosporine
neuron projection arborization
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of branching morphogenesis of a nerve
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
