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Invitrogen
Casc5 Polyclonal Antibody
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产品信息
PA5-49174
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 1557-1583 amino acids from the C-terminal region of mouse Casc5.
偶联物
形式
Liquid
浓度
0.37 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cancer susceptibility candidate gene 5 protein homolog; Kinetochore scaffold 1; Kinetochore-null protein 1; Outer kinetochore KNL1 complex subunit KNL1; Protein CASC5
基因别名: 2310043D08Rik; 5730505K17Rik; Casc5; Knl1
UniProt ID: (Mouse) Q66JQ7
Entrez Gene ID: (Mouse) 76464
