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Invitrogen
Casc5 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-65573
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DVTKQVIQTHV NAGEAPDPVI TSNVPCFHSI KPNLNNLNGK TGEFLAFQTV HLPPLPEQLL ELGNKAHNDM HIVQATEIHN INIISSNAKD SRDEENKKSH NGAETTSLPP KTVFKDKVRR CSLGIFLPRL PNKRNCSVTG IDDLEQ
Highest antigen sequence identity to the following orthologs - mouse 60%, rat 60%.
靶标信息
Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AF15q14; ALL1-fused gene from chromosome 15q14 protein; Blinkin; Bub-linking kinetochore protein; Cancer susceptibility candidate gene 5 protein; Cancer/testis antigen 29; CT29; Kinetochore scaffold 1; Kinetochore-null protein 1; Outer kinetochore KNL1 complex subunit KNL1; Protein CASC5; Protein D40/AF15q14
基因别名: CASC5; KIAA1570; KNL1
Entrez Gene ID: (Human) 57082
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
