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Invitrogen
Caspase 2 Precursor Recombinant Rabbit Monoclonal Antibody (2Z10F1)
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Caspase 2 Precursor Antibody (MA5-35599) in WB
Western blot analysis of Caspase 2 Precursor in extracts of various cell lines. Samples were incubated with Caspase 2 Precursor Monoclonal antibody (Product # MA5-35599) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Jurkat cells were treated by Staurosporine (1 µM) for 3 hours. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-35599
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2Z10F1
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 334-452 of human Caspase-2 (P29594)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.05 mg/mL
规格
205 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GKNHTQSPGC EESDAGKEEL MKMRLPTRSD MICGYACLKG NAAMRNTKRG SWYIEALTQV FSERACDMHV ADMLVKVNAL IKEREGYAPG TEFHRCKEMS EYCSTLCQQL YLFPGYPPT
靶标信息
Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CASP-2; Caspase-2; ICH-1L; ICH-1L/1S; NEDD-2; Neural precursor cell expressed developmentally down-regulated protein 2; Protease ICH-1
基因别名: CASP2; ICH1; NEDD2
Entrez Gene ID: (Human) 835
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