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Invitrogen
Caspase 6 Polyclonal Antibody
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Caspase 6 Antibody (PA5-110766) in IHC (P)
Immunohistochemical analysis of Caspase 6 in human small intestine and skeletal muscle tissues using Caspase 6 Polyclonal Antibody (Product # PA5-110766) using Anti-CASP6 antibody. Corresponding CASP6 RNA-seq data are presented for the same tissues.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-110766
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DVPVIPLDVV DNQTEKLDTN ITEVDAASVY TLPAGADFLM CYSVAEGYYS HRETVNGSWY IQDLCEMLGK YGSSLEFTEL LTLVNRKVSQ RRVDFCKDPS AIGKKQV
Highest antigen sequence indentity to the following orthologs: Mouse - 91%, Rat - 91%.
靶标信息
Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Apoptotic protease Mch-2; CASP-6; Caspase-6; mCASP-6
基因别名: CASP6; MCH2
Entrez Gene ID: (Human) 839
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