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Invitrogen
Caspase 9 (Cleaved Asp330) Polyclonal Antibody
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Caspase 9 (Cleaved Asp330) Antibody (PA5-77889) in WB
Western Blot using Caspase 9 (Cleaved Asp330) Polyclonal Antibody (Product # PA5-77889). Untreated (–) and treated (+) Jurkat whole cell extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with Caspase 9 (Cleaved Asp330) Polyclonal Antibody (Product # PA5-77889) diluted at 1:500.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-77889
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Caspase 9 (cleaved Asp330). The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.73 mg/mL
规格
273 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: Jurkat (10 µM Etoposide treatment for 24 hr)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Caspase 9 (Cleaved Asp330) encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: APAF-3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; CASP-9; Caspase-9; ICE-LAP6; ICE-like apoptotic protease 6
基因别名: CASP9; MCH6
Entrez Gene ID: (Human) 842
Disclaimer
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