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Osenses
Cathelicidin Monoclonal Antibody (OSX12)
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Cathelicidin Antibody (OSC00155G-100UG) in ICC/IF
Staining of a cytospin preparation of peripheral blood mononuclear cells (PBMC) isolated from buffycoat. Cells were left to air dry and then fixed with cold acetone (90 seconds) and blocked with PBS containing 1% FCS and 0.1% saponin (blocking buffer) for 20 minutes. Cells were then washed twice in PBS and incubated with Mouse monoclonal to Cathelicidin: OSX12 clone (OSC00155G) at a concentration of 10 µg/m... View More
产品信息
OSC00155G-100UG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG, kappa
分类
Monoclonal
类型
Antibody
克隆号
OSX12
抗原
A synthetic peptide from human Cathelicidin antimicrobial peptide (LL-37) conjugated to an immunogenic carrier protein has been used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
纯化类型
Ammonium sulfate precipitation
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Cathelicidin antimicrobial peptide.
靶标信息
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 18 kDa cationic antimicrobial protein; CAP-18; Cathelicidin antimicrobial peptide; hCAP-18; hCAP18
基因别名: CAMP; CAP-18; CAP18; CRAMP; FALL-39; FALL39; HSD26; LL37
UniProt ID: (Human) P49913
Entrez Gene ID: (Human) 820
