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Invitrogen
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This antibody detects human pro and active Cathepsin E in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 40% cross-reactivity with recombinant mouse Cathepsin E is observed and less than 2% cross-reactivity with recombinant human (rh) Cathepsin D and rhBACE is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Cathepsin E may have a role in immune function. It is most likely involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. It may also play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cathepsin E; EC 3.4.23.34; erythrocyte membrane aspartic proteinase; slow-moving proteinase
基因别名: CATE; CTSE
UniProt ID: (Human) P14091
Entrez Gene ID: (Human) 1510