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Invitrogen
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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin O maintains the structural features characteristic of other cysteine proteinases including the active site cysteine residue that is involved in covalent intermediate formation during peptide hydrolysis. Cathepsin O is an endoproteinase that may be involved in extracellular matrix degradation. Cathepsin O is abundantly expressed in the ovary, kidney and placenta with lower levels found in thymus and skeletal muscle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cathepsin O; similar to cathepsin O
基因别名: A330105D01Rik; A430056C07; AI118514; CTSO; CTSO1
UniProt ID: (Human) P43234, (Mouse) Q8BM88
Entrez Gene ID: (Human) 1519, (Mouse) 229445, (Rat) 684529