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Invitrogen
Cathepsin S Polyclonal Antibody
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Product Details
PA5-82049
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
C. elegans
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CTSS. Recombinant protein control fragment (Product #RP-100380).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NGGFMTTAFQ YIIDNKGIDS DASYPYKAMD QKCQYDSKYR AATCSKYTEL PYGREDVLKE AVANKGPVSV GVDARHPSFF LYRSGVYYEP SCTQNVNHGV LVVGYGDLNG KEYWLVKNSW GHNFGEEGYI RMARNKGNHC G
Highest antigen sequence indentity to the following orthologs: Rat - 78%, Mouse - 76%.
Target Information
The protein CTSS, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The protein can function as an elastase over a broad pH range in alveolar macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cathepsin S
Gene Aliases: CTSS
UniProt ID: (Human) P25774
Entrez Gene ID: (Human) 1520
toll-like receptor signaling pathway
adaptive immune response
proteolysis
immune response
response to acidic pH
protein processing
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class II
extracellular matrix disassembly
collagen catabolic process
basement membrane disassembly
antigen processing and presentation of peptide antigen
proteolysis involved in cellular protein catabolic process
cellular response to thyroid hormone stimulus
positive regulation of cation channel activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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