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Invitrogen
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Recommended positive controls: mouse heart.
Predicted reactivity: Mouse (89%), Rat (87%), Rhesus Monkey (99%), Bovine (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Binder of Rho GTPases 1; CDC42 effector protein (Rho GTPase binding) 2; Cdc42 effector protein 2; CRIB-containing BOGR1 protein
基因别名: 1110008C05Rik; BORG1; CDC42EP2; CEP2; D19Bwg1013e
UniProt ID: (Human) O14613, (Mouse) Q8JZX9
Entrez Gene ID: (Human) 10435, (Mouse) 104252