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Invitrogen
Cdc42EP5 Polyclonal Antibody
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产品信息
PA5-106637
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CDC42EP5(Accession Q6NZY7), corresponding to amino acid residues M1-R38.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total BORG3.
靶标信息
Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: binder of Rho GTPase 3; Binder of Rho GTPases 3; CDC42 effector protein (Rho GTPase binding) 5; Cdc42 effector protein 5; CRIB-containing BORG3 protein
基因别名: 1700027J19Rik; 2010007O02Rik; BORG3; C85526; CDC42EP5; CEP5
UniProt ID: (Human) Q6NZY7, (Mouse) Q9Z0X0
Entrez Gene ID: (Human) 148170, (Mouse) 58804
