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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total BORG3.
Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: binder of Rho GTPase 3; Binder of Rho GTPases 3; Cdc42 effector protein 5; CRIB-containing BORG3 protein
基因别名: 1700027J19Rik; 2010007O02Rik; Borg3; C85526; Cdc42ep5; CEP5
UniProt ID: (Mouse) Q9Z0X0
Entrez Gene ID: (Mouse) 58804