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Invitrogen
Chp Monoclonal Antibody (JCC1)
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产品信息
MA1-40273
应用
建议稀释比
已发表文章
产品规格
种属反应
Bacteria
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
JCC1
抗原
CHIPS C-Terminus.
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Protein G
保存液
PBS with 0.1% BSA
内含物
no preservative
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-40273 detects CHIPS from S. aureus samples.
MA1-40273 has been successfully used in flow cytometry, ELISA, immunohistochemistry (frozen), immunohistochemistry (paraffin), and Western blot applications.
The MA1-40273 immunogen is the C-terminus of CHIPS.
靶标信息
The bacterial pathogen Staphylococcus aureus is insensitive to antimicrobial host defense peptides such as defensins, protegrins, platelet microbicidal proteins and bacteriocins. Staphylococci have developed various resistance mechanisms including those specific for bacteriocins and several host defense peptides. A protein belonging to the resistance mechanism of Staphylococcus aureus is known as CHIPS (Chemotaxis Inhibiting Protein of Staphylococcus aureus). CHIPS is a protein produced by Staphylococcus aureus that inhibits chemotaxis of neutrophils by blocking the Formyl Peptide Receptor (FPR) and C5a Receptor on neutrophils. CHIPS and antibodies against CHIPS can be useful for various experimental infection models of Staphylococcus aureus. Furthermore these reagents can be of help in studies on the role of FPR and C5a in inflammatory processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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