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Invitrogen
Chromogranin C Polyclonal Antibody
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产品信息
PA5-110343
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 30-320 of human SCG2 (NP_003460.2).
偶联物
形式
Liquid
浓度
0.67 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FQRNQLLQKE PDLRLENVQK FPSPEMIRAL EYIENLRQQA HKEESSPDYN PYQGVSVPLQ QKENGDESHL PERDSLSEED WMRIILEALR QAENEPQSAP KENKPYALNS EKNFPMDMSD DYETQQWPER KLKHMQFPPM YEENSRDNPF KRTNEIVEEQ YTPQSLATLE SVFQELGKLT GPNNQKRERM DEEQKLYTDD EDDIYKANNI AYEDVVGGED WNPVEEKIES QTQEEVRDSK ENIEKNEQIN DEMKRSGQLG IQEEDLRKES KDQLSDDVSK VIAYLKRLVN A
靶标信息
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chromogranin C (Secretogranin II); Chromogranin-C; secretogranin 2; Secretogranin II; secretogranin II (chromogranin C); Secretogranin-2; secretoneurin; SgII
基因别名: Chcg; CHGC; EM66; Scg-2; SCG2; SgII; SN
UniProt ID: (Human) P13521, (Rat) P10362
Entrez Gene ID: (Human) 7857, (Rat) 24765
MAPK cascade
angiogenesis
negative regulation of endothelial cell proliferation
positive regulation of endothelial cell proliferation
inflammatory response
protein secretion
intracellular signal transduction
endothelial cell migration
eosinophil chemotaxis
positive chemotaxis
induction of positive chemotaxis
negative regulation of endothelial cell apoptotic process
negative regulation of extrinsic apoptotic signaling pathway
