Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Chromogranin C Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 4
Chromogranin C Antibody (PA5-22371) in IHC (P)
Chromogranin C Polyclonal Antibody detects SCG2 protein at cytosol on rat RT2 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded rat RT2 xenograft. Chromogranin C Polyclonal Antibody (Product # PA5-22371) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-22371
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Dog
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Chromogranin C. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.51 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: NT2D1, IMR32, U87-MG.
Predicted reactivity: Human (99%), Pig (84%), Rhesus Monkey (96%), Bovine (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Chromogranin C (Secretogranin II); Chromogranin-C; secretogranin 2; Secretogranin II; secretogranin II (chromogranin C); Secretogranin-2; secretoneurin; SgII
基因别名: Chcg; CHGC; EM66; Scg-2; SCG2; SgII; SN
UniProt ID: (Human) P13521, (Mouse) Q03517, (Rat) P10362
Entrez Gene ID: (Human) 7857, (Mouse) 20254, (Rat) 24765
MAPK cascade
angiogenesis
positive regulation of endothelial cell proliferation
intracellular signal transduction
eosinophil chemotaxis
positive chemotaxis
induction of positive chemotaxis
negative regulation of endothelial cell apoptotic process
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of endothelial cell proliferation
inflammatory response
protein secretion
endothelial cell migration
