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Invitrogen
Clarithromycin Recombinant Mouse Monoclonal Antibody (2D3)
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Clarithromycin Antibody (MA566571) in SDS-PAGE
SDS-PAGE characterization of Clarithromycin under reducing conditions. Lane M: Protein marker (kDa); Lane CTM: Purified Clarithromycin Recombinant Monoclonal (Product # MA566571). Clarithromycin showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-408.
产品信息
MA566571
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2D3
抗原
Conjugate of CTM hapten and KLH.
偶联物
形式
Liquid
浓度
2.7 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Clarithromycin is a semisynthetic macrolide antibiotic derived from erythromycin, characterized by the addition of a methyl group at the C-6 hydroxyl position, which enhances its acid stability and clinical efficacy. This modification allows clarithromycin to be effective against a broad spectrum of bacterial infections, including respiratory tract infections, skin infections, and Helicobacter pylori infection. Structurally, clarithromycin belongs to the 14-membered macrolide class, and its derivatives have been synthesized to improve antibacterial activity against resistant strains. The gene information related to clarithromycin involves its biosynthesis and the genetic encoding of biosensors that report its activity, highlighting its role in combating bacterial resistance. Clarithromycin's functionality is primarily attributed to its ability to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and proliferation of bacteria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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