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This antibody is predicted to react with bovine, canine, and mouse based on sequence homology.
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is brain, skeletal muscle or ovarian carcinoma.
Claudin proteins are a family of proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact; made up of network of strands to act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Claudin-10; Oligodendrocyte-specific protein-like; OSP-like; OSP-like protein
基因别名: CLDN10; CPETRL3; OSP-L
UniProt ID: (Human) P78369
Entrez Gene ID: (Human) 9071