Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Clonidine Recombinant Mouse Monoclonal Antibody (2E7)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
Clonidine Antibody (MA566564) in SDS-PAGE
SDS-PAGE characterization of Clonidine under reducing conditions. Lane M: Protein marker (kDa); Lane CLO: Purified Clonidine Recombinant Monoclonal (Product # MA566564). Clonidine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-264.
产品信息
MA566564
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2E7
抗原
Conjugate of CLO hapten and KLH.
偶联物
形式
Liquid
浓度
4.5 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Clonidine is an alpha-2 adrenergic receptor agonist primarily used for its antihypertensive properties. It binds to receptors located in the substantia gelatinosa and the intermediolateral cell column, leading to the inhibition of substance P release and suppression of wide dynamic range neuron firing in the spinal cord dorsal horn. Structurally, clonidine hydrochloride forms strong hydrogen bonds between NH groups and Cl ions, as observed through X-ray diffraction studies. The metabolism of clonidine is influenced by genetic polymorphisms, particularly within the CYP2D6 gene, which affects its metabolic rate and efficacy. Research has also explored clonidine's delivery via transferrin-conjugated PLGA nanoparticles for enhanced brain targeting, demonstrating its versatile application in therapeutic settings.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
