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Fabgennix
Cofilin Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
CFL-101AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 120-166 on human Cofilin protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Cofilin binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 18 kDa phosphoprotein; CFL-1; COF1; Cofilin, non-muscle isoform; Cofilin-1; Cofilin1; p18
基因别名: AA959946; CFL; CFL1; Cof; n-cofilin
UniProt ID: (Rat) P45592, (Mouse) P18760
Entrez Gene ID: (Rat) 29271, (Mouse) 12631
mitotic cytokinesis
neural crest cell migration
neural fold formation
protein phosphorylation
protein import into nucleus
cytoskeleton organization
actin filament organization
response to virus
regulation of cell morphogenesis
establishment of cell polarity
cell projection organization
actin filament depolymerization
positive regulation of actin filament depolymerization
response to amino acid
negative regulation of cell size
regulation of dendritic spine morphogenesis
movement of cell or subcellular component
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