Invitrogen

Complement C4 Polyclonal Antibody

Name: Complement C4 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-119047

1 篇参考文献

查看其他9个Complement C4抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

Complement C4 Antibody in Western Blot (WB)

图: 1 / 2

Complement C4 Antibody (PA5-119047) in WB

Western blot analysis of Complement C4 in HepG2 cell lysate using Complement C4 Polyclonal Antibody (Product # PA5-119047) at a dilution of 5 µg/mL. Secondary antibody used is HRP-Goat anti-Rabbit IgG polyclonal antibody at a dilution of 0.2 µg/mL.

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Immunogen Image Complement C4 Polyclonal Antibody

产品信息

PA5-119047

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.01-5 µg/mL

酶联免疫吸附实验 (ELISA)

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产品规格

种属反应

Human, Mouse

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein Complement Component 4. The antigen corresponds to amino acid range 1450-1723 of the target protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Antigen affinity chromatography, Protein A

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.05% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2903547

靶标信息

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: acidic C4; Acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; c4 complement; C4A anaphylatoxin; Chido form of C4; Complement C4-A; Complement C4-B; complement C4B1a; complement component 4 (within H-2S); complement component 4B (Childo blood group); DADB-112B14.11; DAMC-258G8.6; FLJ60561; MGC164979; MHC class III region complement; Rodgers form of C4; sex-limited protein

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基因别名: C4; C4A; C4A2; C4A3; C4A4; C4A6; C4AD; C4B; C4B1; C4B12; C4B2; C4B3; C4B5; C4B_2; C4BD; C4F; C4S; CH; CO4; CPAMD2; CPAMD3; RG; Slp; Ss