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Invitrogen
Complement C4 Monoclonal Antibody (16D2)
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产品信息
MA1-40047
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
Mouse
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
16D2
抗原
Thymocytes decorated with Thy-1 antibody and complement components
偶联物
形式
Liquid
浓度
100 µg/mL
纯化类型
Protein G
保存液
PBS with 0.1% BSA
内含物
0.02% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-40047 detects C4 from mouse samples.
MA1-40047 has been successfully used in immunohistochemistry (frozen), immunoprecipitation, ELISA, immunofluorescence and Western blot applications.
The MA1-40047 immunogen is mouse complement factor C4.
Suggested positive Control: T-cell regions of Mouse spleen.
靶标信息
This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: c4 complement; Complement C4-B; complement component 4 (within H-2S); complement component 4B (Childo blood group); DADB-112B14.11; DAMC-258G8.6; FLJ60561; MGC164979; sex-limited protein
基因别名: C4; C4b; Slp; Ss
UniProt ID: (Mouse) P01029
Entrez Gene ID: (Mouse) 625018, (Mouse) 12268
