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Invitrogen
Connexin 50 Polyclonal Antibody
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产品信息
PA5-120672
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 234-433 of human GJA8 (NP_005258.2).
偶联物
形式
Liquid
浓度
0.63 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: Raji.
Immunogen sequence: SALKRPVEQP LGEIPEKSLH SIAVSSIQKA KGYQLLEEEK IVSHYFPLTE VGMVETSPLP AKPFNQFEEK ISTGPLGDLS RGYQETLPSY AQVGAQEVEG EGPPAEEGAE PEVGEKKEEA ERLTTEEQEK VAVPEGEKVE TPGVDKEGEK EEPQSEKVSK QGLPAEKTPS LCPELTTDDA RPLSRLSKAS SRARSDDLTV
靶标信息
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha 8 connexin; cell surface glycoprotein; connexin 50; Connexin-50; Cx50; gap junction alpha 8; Gap junction alpha-8 protein; gap junction membrane channel protein alpha 8; gap junction membrane channel protein alpha-8; gap junction protein alpha 8 50kDa; Lens fiber protein MP70; lens intrinsic membrane protein MP70; lens opacity 10
基因别名: Aey5; CAE; CAE1; Cnx50; CTRCT1; CX50; CZP1; GJA8; Lop10; MP70
UniProt ID: (Human) P48165, (Mouse) P28236
Entrez Gene ID: (Human) 2703, (Rat) 29601, (Mouse) 14616
