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Positive test controls include: HL-60, SW480, Mouse brain, Mouse lung, Rat lung. The target is usually found in the following locations: Cytoplasm, Cytoplasmic vesicle, cell cortex, cytoskeleton, phagosome membrane.
Immunogen sequence: DLYPPTAGPD PALTAEEWLG GRDAGPLLIS LKDGYVPPKS RELRVNRGLD TGRRRAAPEA SGTPSSDAVS RLEEEMRKLQ ATVQELQKRL DRLEETVQAK
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: actin-binding; Clabp coronin; Clipin-A; coronin 1; coronin, actin binding protein, 1A; coronin-1; Coronin-1A; coronin-like actin binding protein; Coronin-like protein A; Coronin-like protein p57; FLJ41407; MGC117380; TACO; Tryptophan aspartate-containing coat protein
基因别名: CLABP; CLIPINA; CORO1; CORO1A; HCORO1; IMD8; Lmb3; p57; TACO
UniProt ID: (Human) P31146, (Mouse) O89053, (Rat) Q91ZN1
Entrez Gene ID: (Human) 11151, (Mouse) 12721, (Rat) 155151
分子生物学功能: non-motor actin binding protein