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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: WRSSSLLEEK MPRWAAEHRL EEKKTWLTNG FDVFECPPPK TENELLQMFY RQQEEIRRLR ELLTQREVQA KQ
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coronin-2A; IR10; WD repeat-containing protein 2
基因别名: CORO2A; IR10; WDR2
Entrez Gene ID: (Human) 7464