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Invitrogen
Cullin 7 Polyclonal Antibody
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产品信息
PA5-114724
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CUL7(Accession Q14999), corresponding to amino acid residues C1405-E1455.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CUL7.
靶标信息
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CUL-7; Cullin-7; p185; p193
基因别名: 2510004L20Rik; 3M1; AA409809; C230011P08Rik; CUL7; dJ20C7.5; KIAA0076; p185; p193
UniProt ID: (Human) Q14999, (Mouse) Q8VE73
Entrez Gene ID: (Human) 9820, (Mouse) 66515
microtubule cytoskeleton organization
mitotic cytokinesis
vasculogenesis
epithelial to mesenchymal transition
placenta development
ubiquitin-dependent protein catabolic process
apoptotic process
Golgi organization
regulation of mitotic nuclear division
protein ubiquitination
regulation of apoptotic process
regulation of endothelial cell differentiation
positive regulation of dendrite morphogenesis
proteolysis
viral process
IRE1-mediated unfolded protein response
