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Invitrogen
Cusatuzumab Humanized Recombinant Human Monoclonal Antibody
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Cusatuzumab Humanized Antibody (MA5-59009) in Flow
Flow cytometry analysis of Cusatuzumab Recombinant monoclonal antibody (Product # MA5-59009). HL-60 cells were stained with (cusatuzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.2727 µg/mL.
产品信息
MA5-59009
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Protein A
保存液
25mM histidine, pH 6.2, with 8% sucrose, 0.01% Tween 80
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
靶标信息
Cusatuzumab is an experimental SIMPLE antibody that targets CD70, which is an immune checkpoint target involving hematological malignancies, a variety of solid tumors, and a variety of autoimmune diseases. Cusatuzumab aims to block CD70 by targeting complement-dependent cytotoxicity, enhancing antibody-dependent cell-mediated phagocytosis, and enhancing antibody-dependent cell-mediated cytotoxicity, killing CD70-expressing cancer cells, and recovering Immune monitoring of solid tumors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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