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Invitrogen
Cyclin D2 Monoclonal Antibody (DCS3.1)
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Cyclin D2 Antibody (MA1-12297) in WB
Journal of diabetes investigation 2019 -
Figure 7 Insulin secretion and change in messenger ribonucleic acid expression levels in MIN 6-K8 beta-cells. (a) Effects of glucose, glimepiride and nifedipine on insulin secretion in MIN 6-K8 beta-cells. Insulin secretion from MIN 6-K8 beta-cells was normalized by cellular insulin content ( n = 7 per group). (b, c) Messenger ribonucleic acid expression levels of cyclinD2 and Irs2 in MIN 6-K8 beta-cells ( ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA1-12297
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Avian,
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
DCS3.1
抗原
His-tagged recombinant full-length Cyclin D2
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Ammonium sulfate precipitation
保存液
PBS
内含物
0.08% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Cyclin D2 is a G1 cyclin required for G1 phase progression and is a strong candidate for a proto-oncogene. Cyclin D2 can phosphorylate pRB when associated with cdk 4 and / or cdk 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Ccnd2; KIAK0002; MGC102758; unnamed protein product; vin-1 proto-oncogene
基因别名: 2600016F06Rik; cD2; KIAK0002; MPPH3; Vin-1; Vin1
UniProt ID: (Human) P30279, (Mouse) P30280, (Rat) Q04827
Entrez Gene ID: (Human) 894, (Mouse) 12444, (Rat) 64033
G1/S transition of mitotic cell cycle
positive regulation of cell proliferation
negative regulation of apoptotic process
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of mitotic cell cycle phase transition
regulation of G1/S transition of mitotic cell cycle
long-term memory
adult locomotory behavior
positive regulation of epithelial cell proliferation
regulation of cell cycle
positive regulation of cardiac muscle cell proliferation
cellular response to X-ray
negative regulation of cardiac muscle cell differentiation
ovarian follicle development
liver development
spermatogenesis
response to follicle-stimulating hormone
response to estradiol
cellular response to insulin stimulus
response to testosterone
response to genistein
response to peptide hormone
response to estrogen
response to human chorionic gonadotropin
response to ethanol
regulation of neuron differentiation
response to cAMP
cellular response to follicle-stimulating hormone stimulus
cellular response to growth hormone stimulus
cellular response to testosterone stimulus
cellular response to dexamethasone stimulus
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