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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Cytochrome C Antibodies

          Invitrogen

          Cytochrome C Polyclonal Antibody

          2 篇参考文献
          查看其他50个Cytochrome C抗体

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          说明书
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          Cite Cytochrome C Polyclonal Antibody

          Cytochrome C Polyclonal Antibody

          产品信息

          PA1-9586

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1:2,000-1:10,000
          查看2篇已发表文章 2篇已发表文章

          酶联免疫吸附实验 (ELISA)

          1:2,000-1:10,000
          -
          产品规格

          种属反应

          Bovine, Human, Mouse, Rat

          已发表种属

          Human

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          Purified bovine cytochrome c protein
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          1 mg/mL

          纯化类型

          Affinity chromatography

          保存液

          PBS

          内含物

          0.02% sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2230390

          产品详细信息

          PA1-9586 detects Cytochrome C in human, mouse, bovine and rat samples.

          PA1-9586 has been successfully used in Western blot and ELISA procedures. By Western blot, PA1-9586 detects a 12 kDa protein representing Cytochrome C. Do not use dry milk in blocking or dilution buffer in your assay. Use BSA (3-5% in blocking and 1-3% in dilution buffers) in your assay.

          PA1-9586 immunogen is a purified bovine cytochrome c protein

          Store at 4°C for 1 week, and -20°C for up to one year.

          靶标信息

          Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          生物信息学

          蛋白别名: CRF; Cytochrome c; Cytochrome C, expressed in somatic tissues; Cytochrome c, somatic; hc1

          查看更多 收起

          基因别名: CYC; CYCS; CYCSA; cytc; HCS; THC4

          查看更多 收起

          UniProt ID: (Bovine) P62894, (Human) P99999, (Mouse) P62897, (Rat) P62898

          查看更多 收起

          Entrez Gene ID: (Bovine) 510767, (Human) 54205, (Mouse) 13063, (Rat) 25309

          查看更多 收起

          功能
          electron carrier activity heme binding metal ion binding protein serine/threonine phosphatase activity protein binding electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity iron ion binding lipid binding
          参与通路
          apoptotic process response to reactive oxygen species mitochondrial electron transport, ubiquinol to cytochrome c mitochondrial electron transport, cytochrome c to oxygen protein dephosphorylation mitochondrion organization activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c cellular respiration intrinsic apoptotic signaling pathway apoptotic DNA fragmentation hydrogen peroxide metabolic process ATP synthesis coupled electron transport response to ischemia response to oxidative stress negative regulation of hydrogen peroxide biosynthetic process glial cell apoptotic process positive regulation of cellular respiration
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

          了解更多
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