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          • Primary Antibodies ›
          • CYP1A1/CYP1A2 Antibodies

          NeoBiotechnologies

          Cytochrome P450 1A1/1A2 Monoclonal Antibody (MC1)

          查看其他4个CYP1A1/CYP1A2抗体

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          Cite Cytochrome P450 1A1/1A2 Monoclonal Antibody (MC1)

          • 抗体检测数据 (1)
          Cytochrome P450 1A1/1A2 Antibody in SDS-PAGE (SDS-PAGE)
          Group 53 Created with Sketch.
          Cytochrome P450 1A1/1A2 Antibody in SDS-PAGE (SDS-PAGE)
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          图: 1 / 1

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          Cytochrome P450 1A1/1A2 Antibody (1543-MSM1-P0) in SDS-PAGE

          SDS-PAGE analysis Purified Cytochrome P450 1A1/1A2 Mouse Monoclonal Antibody (MC1). Confirmation of Purity and Integrity of Antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
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          Cytochrome P450 1A1/1A2 Antibody in SDS-PAGE (SDS-PAGE)
          Cytochrome P450 1A1/1A2 Monoclonal Antibody (MC1)

          产品信息

          1543-MSM1-P0

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1-2 µg/mL
          -

          免疫组织化学(多聚甲醛固定) (IHC (PFA))

          0.25-0.5 µg/mL
          -

          免疫细胞化学 (ICC/IF)

          2-4 µg/mL
          -
          产品规格

          种属反应

          Human, Mouse, Non-human primate, Rat

          宿主/亚型

          Mouse / IgG1, kappa

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          MC1

          抗原

          3-methylcholanthrene induced rat cytochrome P450 protein.
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          200 µg/mL

          纯化类型

          Protein A/G

          保存液

          PBS, pH 7.4, with 0.05% BSA

          内含物

          0.05% sodium azide

          保存条件

          4°C, do not freeze

          运输条件

          Ambient (domestic); Wet ice (international)

          靶标信息

          This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: aromatic compound inducible; aryl hydrocarbon hydroxylase; Cholesterol 25-hydroxylase; CYP1A1; CYPIA1; CYPIA2; Cytochrome P(3)450; Cytochrome P-448; Cytochrome P-450d; cytochrome P1-450; cytochrome P1-450, dioxin-inducible; Cytochrome P3 450; Cytochrome P450 1A1; Cytochrome P450 1A2; Cytochrome P450 4; cytochrome P450 family 1 subfamily a polypeptide 1; cytochrome P450 family 1 subfamily a polypeptide 2; Cytochrome P450 form 6; cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c); Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d); cytochrome P450 subfamily I, polypeptide 1; cytochrome P450, 1a1; cytochrome P450, 1a1, aromatic compound inducible; cytochrome P450, 1a2; cytochrome P450, 1a2, aromatic compound inducible; cytochrome P450, family 1, subfamily A, polypeptide 1; cytochrome P450, family 1, subfamily A, polypeptide 2; cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c); cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d); cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2; Cytochrome P450-C; Cytochrome P450-D; Cytochrome P450-P1; Cytochrome P450-P2; Cytochrome P450-P3; Cytochrome P450MT2; dioxin-inducible; dioxin-inducible P3-450; flavoprotein-linked monooxygenase; Hydroperoxy icosatetraenoate dehydratase; microsomal monooxygenase; P-448; P450 form 4; P450-D; P450form6; P450MT2; xenobiotic monooxygenase

          查看更多 收起

          基因别名: AHH; AHRR; CP11; CP12; CYP1; Cyp1a-1; Cyp1a-2; CYP1A1; CYP1A2; Cyp45c; Cypc45c; CYPD45; CYPIA1; P-450d; P-450MC; P1-450; P3-450; P450(PA); P450-1; P450-3; P450-C; P450DX; RATCYPD45

          查看更多 收起

          UniProt ID: (Human) P04798, (Human) P05177, (Mouse) P00184, (Rat) P00185, (Mouse) P00186, (Rat) P04799

          查看更多 收起

          Entrez Gene ID: (Human) 1543, (Human) 1544, (Mouse) 13076, (Rat) 24296, (Mouse) 13077, (Rat) 24297

          查看更多 收起

          功能
          monooxygenase activity iron ion binding protein binding steroid hydroxylase activity oxidoreductase activity oxidoreductase activity, acting on diphenols and related substances as donors flavonoid 3'-monooxygenase activity oxygen binding enzyme binding heme binding demethylase activity aromatase activity vitamin D 24-hydroxylase activity electron carrier activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen caffeine oxidase activity catalytic activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen metal ion binding oxidoreductase oxygenase metabolite interconversion enzyme
          参与通路
          response to hypoxia porphyrin-containing compound metabolic process aging cell proliferation amine metabolic process response to wounding response to virus response to nematode response to herbicide ethylene metabolic process embryo development ending in birth or egg hatching coumarin metabolic process flavonoid metabolic process response to iron(III) ion insecticide metabolic process drug metabolic process dibenzo-p-dioxin catabolic process epoxygenase P450 pathway response to food response to lipopolysaccharide response to vitamin A response to immobilization stress vitamin D metabolic process response to drug 9-cis-retinoic acid biosynthetic process camera-type eye development response to antibiotic response to arsenic-containing substance digestive tract development hydrogen peroxide biosynthetic process response to hyperoxia oxidation-reduction process maternal process involved in parturition hepatocyte differentiation demethylation cellular response to organic cyclic compound omega-hydroxylase P450 pathway positive regulation of G1/S transition of mitotic cell cycle steroid catabolic process xenobiotic metabolic process toxin biosynthetic process post-embryonic development alkaloid metabolic process regulation of gene expression monoterpenoid metabolic process dibenzo-p-dioxin metabolic process lung development methylation response to estradiol monocarboxylic acid metabolic process drug catabolic process exogenous drug catabolic process cellular respiration heterocycle metabolic process oxidative demethylation cellular response to cadmium ion oxidative deethylation toxin metabolic process response to toxic substance liver development response to organic substance response to organic cyclic compound developmental process cellular aromatic compound metabolic process
          It has to be done as per old AB suggested Products section.
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