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Invitrogen
Cytoglobin Polyclonal Antibody
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Cytoglobin Antibody (PA5-79122) in IHC (P)
Immunohistochemistry analysis of Cytoglobin on paraffin-embedded human intestinal cancer tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with Cytoglobin polyclonal antibody (Product# PA5-79122) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minu... View More
产品信息
PA5-79122
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human Cytoglobin recombinant protein (Position: M1-P190).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat small intestine tissue, mouse small intestine tissue. IHC: mouse intestine tissue, mouse cardiac muscle tissue, rat intestine tissue, human intestinal cancer tissue, human lung cancer tissue.
靶标信息
Cytoglobin is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress (Trent and Hargrove, 2002).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytoglobin; HGb; Histoglobin; Nitric oxygen dioxygenase; Nitric oxygen dioxygenase CYGB; Nitrite reductase CYGB; NOD; Pseudoperoxidase CYGB; stellate cell activation associated protein; Stellate cell activation-associated protein; Superoxide dismutase CYGB
基因别名: 3110001K20Rik; CYGB; HGB; Staap; STAP
UniProt ID: (Human) Q8WWM9, (Mouse) Q9CX80, (Rat) Q921A4
Entrez Gene ID: (Human) 114757, (Mouse) 114886, (Rat) 170520
transport
response to oxidative stress
negative regulation of fibroblast migration
oxygen transport
fatty acid oxidation
negative regulation of collagen biosynthetic process
oxidation-reduction process
negative regulation of hepatic stellate cell activation
response to hypoxia
regulation of nitric-oxide synthase activity
cellular oxidant detoxification
