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产品信息
PA5-85864
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within Human Cytokeratin 17 aa 383-432
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 0.2% BSA, 50% Glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2802665
靶标信息
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 39.1; CK-17; CK17; Cytokeratin-17; hard keratin; K17; keratin 17, type I; keratin complex 1, acidic, gene 17; Keratin, type I cytoskeletal 17; Keratin-17; krt17 {ECO:0000250|UniProtKB:Q04695}; Type I keratin Ka17
基因别名: 39.1; CK-17; K17; Ka17; Krt1-17; KRT17; PC; PC2; PCHC1
UniProt ID: (Human) Q04695, (Mouse) Q9QWL7, (Rat) Q6IFU8
Entrez Gene ID: (Human) 3872, (Mouse) 16667, (Rat) 287702
morphogenesis of an epithelium
signal transduction
positive regulation of cell growth
hair follicle morphogenesis
keratinization
intermediate filament organization
positive regulation of translation
positive regulation of hair follicle development
epidermis development
intermediate filament-based process
