Invitrogen

Cytokeratin 5/6 Polyclonal Antibody

Cytokeratin 5/6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Cytokeratin 5/6 Antibody (PA5-116450) in IHC (P)

Immunohistochemical analysis of Cytokeratin 5/6 in a paraffin-embedded human esophagus tissue using a Cytokeratin 5/6 polyclonal antibody (Product #PA5-116450). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary ... View More

Cytokeratin 5/6 Antibody in Western Blot (WB)

Cytokeratin 5/6 Antibody in Flow Cytometry (Flow)

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产品信息

PA5-116450

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:50-1:600

流式细胞分析 (Flow)

1:50-1:100

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide within Human Cytokeratin 5 aa 187-236

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 0.2% BSA, 50% glycerol

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2901082

产品详细信息

Positive controls: A431 cell lysates, human skin tissue, human esophagus tissue, Hela.

靶标信息

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: 58 kDa cytokeratin; 60-kDa keratin; CK-5; CK-6A; CK-6B; CK-6D; cytokeratin 5; cytokeratin 6A; cytokeratin 6B; cytokeratin 6C; cytokeratin 6D; Cytokeratin-5; Cytokeratin-6A; Cytokeratin-6B; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; K6A; K6B; kamp-keratin derived antimicrobial peptide; KDAMP; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6A, , type II; keratin 6A, type II; keratin 6B, type II; keratin complex 2, basic, gene 5; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6b; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6h; keratin, epidermal type II, K6A; keratin, epidermal, type II, K6B; Keratin, type II cytoskeletal 5; Keratin, type II cytoskeletal 6A; Keratin, type II cytoskeletal 6B; Keratin-5; Keratin-6-alpha; keratin-6-beta; Keratin-6A; Keratin-6B; keratin-6C; keratin-like 1 (a type II keratin sequence); krt5; mK6-alpha; mK6-beta; tuftelin interacting protein 8; Type-II keratin Kb10; type-II keratin Kb12; Type-II keratin Kb5; Type-II keratin Kb6

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基因别名: 2310016L08Rik; 3300001P10Rik; AW146334; BB144589; CK-6B; CK-6C; CK-6E; CK5; CK6A; CK6B; CK6C; CK6D; DDD; DDD1; EBS2; K5; K6A; K6B; K6C; K6D; Ker2; Krt2-5; Krt2-6; Krt2-6a; Krt2-6b; Krt2-6c; KRT5; KRT5A; Krt6; KRT6A; KRT6B; KRT6C; KRT6D; KRTL1; mK6[a]; mK6[b]; MK6a; PC2; PC3; PC4; Sak57; Tfip8