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Cytokeratin 5/6 Antibody (MA5-42395) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human esophagus tissue using Cytokeratin 5/6 Monoclonal Antibody (Product # MA5-42395). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the Cytokeratin 5/6 anti... View More
产品信息
MA5-42395
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
A2A12
抗原
Synthetic peptide within Human Cytokeratin 5 aa 340-380
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2911536
产品详细信息
Positive Control: HT-29 cell, human skin tissue, human tonsil tissue, human esophagus tissue, A431 cell.
Subcellular Location: Cytoskeleton.
靶标信息
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 58 kDa cytokeratin; CK-5; CK-6A; CK-6B; CK-6D; cytokeratin 6A; cytokeratin 6B; cytokeratin 6C; cytokeratin 6D; Cytokeratin-5; Cytokeratin-6A; Cytokeratin-6B; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; K6A; K6B; kamp-keratin derived antimicrobial peptide; KDAMP; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6A, , type II; keratin 6A, type II; keratin 6B, type II; keratin K6h; keratin, epidermal type II, K6A; keratin, epidermal, type II, K6B; Keratin, type II cytoskeletal 5; Keratin, type II cytoskeletal 6A; Keratin, type II cytoskeletal 6B; Keratin-5; Keratin-6A; Keratin-6B; keratin-6C; keratin-like 1 (a type II keratin sequence); Type-II keratin Kb10; type-II keratin Kb12; Type-II keratin Kb5; Type-II keratin Kb6
基因别名: CK-6B; CK-6C; CK-6E; CK5; CK6A; CK6B; CK6C; CK6D; DDD; DDD1; EBS2; K5; K6A; K6B; K6C; K6D; KRT5; KRT5A; KRT6A; KRT6B; KRT6C; KRT6D; KRTL1; PC2; PC3; PC4
UniProt ID: (Human) P13647, (Human) P02538, (Human) P04259
Entrez Gene ID: (Human) 3852, (Human) 3853, (Human) 3854
