Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Cytokeratin 8 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 11
Cytokeratin 8 Antibody (PA5-34762) in ICC/IF
Immunofluorescence analysis of Cytokeratin 8 was performed using 70% confluent log phase Caco-2 cells. The cells were fixed with ice-cold acetone at 4°C for 5 minutes and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Cytokeratin 8 Polyclonal Antibody (Product # PA5-34762) at 1:200 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Goat a... View More
产品信息
PA5-34762
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Cytokeratin 8. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.82 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HeLa, HepG2, JC.
Predicted reactivity: Mouse (86%), Rat (85%), Dog (88%), Pig (82%), Rhesus Monkey (99%), Bovine (84%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: CK-8; cytokeratin 8; Cytokeratin endo A; Cytokeratin-8; etID33550.23; etID43142.23; etID43142.8; K8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; Keratin, type II cytoskeletal 8; Keratin-8; Type-II keratin Kb8
基因别名: AA960620; AL022697; AU019895; CARD2; cb186; CK-8; CK8; CYK8; DreK8; EndoA; K2C8; K8; KO; Krt-2.8; Krt2-8; KRT8; sb:cb186; wu:fa20h05; wu:fa95h10; wu:fb96c06; zf-K8; zfk8
UniProt ID: (Human) P05787, (Mouse) P11679, (Zebrafish) Q6NWF6
Entrez Gene ID: (Human) 3856, (Mouse) 16691, (Zebrafish) 797433
cell morphogenesis involved in differentiation
multicellular organism development
tumor necrosis factor-mediated signaling pathway
sarcomere organization
response to hydrostatic pressure
response to other organism
cell differentiation involved in embryonic placenta development
extrinsic apoptotic signaling pathway
hepatocyte apoptotic process
viral process
